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- ASUS Prime H410M-E motherboard is designed to support the 10th Gen Intel Core processors with DDR4 memory up to 128GB with Dual Channel Memory Architecture.
- Prime H410 series is engineered with an array of hybrid fan headers to ensure your rig stays cool and stable under intense workloads. Fan Xpert software provides comprehensive control over system fans.
- Numerous USB ports support high-end rigs loaded with peripherals, including a rear-panel USB Type-A connectors with fast USB 3.2 Gen 1 connectivity for compatible cases.
- ASUS OptiMem technology carefully maps memory signal pathways across different PCB layers to reduce vias and adds shielding zones that significantly reduce crosstalk.

PRIME H410M-E
ASUS Prime series is expertly engineered to unleash the full potential of 10th Gen Intel Core processors. Boasting a robust power design, comprehensive cooling solutions and intelligent tuning options, Prime H410 series motherboards provide daily users and DIY PC builders a range of performance tuning options via intuitive software and firmware features.

M.2
M.2 slot supports data-transfer speeds of up to 16 Gbps via x2 PCI Express 3.0 bandwidth, enabling quicker boot-up and app load times with OS or application drives.

Fan Xpert
Fan Xpert software provides comprehensive control over system fans. Whether cooling with air or water, an Auto-Tuning mode intelligently configures all parameters with single click.

Digi+VRM Control
The Digi+VRM delivers real-time control over voltage droop, automatically switching frequency and power efficiency settings.

Energy Effficiency
The EPU automatically optimizes power consumption and maximizes energy savings with Away mode, that creates an energy saving scenario by shutting down unused I/O controllers.

SafeSlot Core
SafeSlot Core+ is the ASUS-exclusive PCIe slot fortified with a one-piece stainless-steel brace that shields the slot to protect it from damage.

USB 3.2 Gen 1
Numerous USB ports support high-end rigs loaded with peripherals, including a rear-panel USB Type-A connectors with fast USB 3.2 Gen 1 connectivity for compatible cases.
Model | PRIME H410M-E |
CPU Socket | LGA 1200 |
CPU Support | Intel Socket 1200 for 10th Gen Intel Core, Pentium Gold and Celeron Processors Supports Intel 14 nm CPU Supports Intel Turbo Boost Technology 2.0 and Intel Turbo Boost Max Technology 3.0 |
Chipset | Intel H410 |
Memory | 2 x DIMM, Max. 64GB, DDR4 2933/2800/2666/2400/2133 MHz Non-ECC, Un-buffered Memory Dual Channel Memory Architecture Supports Intel Extreme Memory Profile (XMP) OptiMem |
On-Board Graphics support | Integrated Graphics Processor 1 x D-Sub 1 x HDMI 1.4b |
Expansion Slot | Intel 10th Gen Processors 1 x PCIe 3.0 x16 (x16 mode) Intel H410 Chipset 2 x PCIe 3.0 x1 |
LAN | Realtek RTL8111H |
Storage | Total supports 1 x M.2 slots and 4 x SATA 6Gb/s ports Intel H410 Chipset : 1 x M.2 Socket 3, with M Key, type 2242/2260/2280 storage devices support (SATA & PCIE 3.0 X2 mode) 4 x SATA 6Gb/s port(s) |
Audio | Realtek ALC887 7.1-Channel High Definition Audio CODEC Supports : Jack-detection, Multi-streaming, Front Panel Jack-retasking, up to 24-Bit/192kHz playback Audio Feature : LED-illuminated design Audio Shielding Dedicated audio PCB layers Premium Japanese audio capacitors |
USB Ports | Rear USB Port ( Total 4 ) 2 x USB 3.2 Gen 1 port(s)(2 x Type-A) 2 x USB 2.0 port(s)(2 x Type-A) Front USB Port ( Total 6 ) 2 x USB 3.2 Gen 1 port(s) 4 x USB 2.0 port(s) |
I/O Ports | 1 x PS/2 keyboard (purple) 1 x PS/2 mouse (green) 1 x D-Sub 1 x HDMI 1 x LAN (RJ45) port(s) 2 x USB 3.2 Gen 1 Type-A 2 x USB 2.0 3 x Audio jack(s) |
Internal I/O ports | 1 x CPU Fan connector(s) 1 x Chassis Fan connector(s) 1 x USB 3.2 Gen 1(up to 5Gbps) connector(s) support(s) additional 2 USB 3.2 Gen 1 port(s) 2 x USB 2.0 connector(s) support(s) additional 4 USB 2.0 port(s) 1 x M.2 Socket 3 with M Key, type 2242/2260/2280 storage devices support (SATA & PCIE 3.0 X2 mode) 1 x COM port(s) connector(s) 4 x SATA 6Gb/s connector(s) 1 x S/PDIF out header(s) 1 x 24-pin EATX Power connector(s) 1 x 8-pin EATX 12V Power connectors 1 x Front panel audio connector(s) (AAFP) 1 x Clear CMOS jumper(s) 1 x System panel connector 1 x Speaker connector |
Accessories | I/O Shield 2 x SATA 6Gb/s cable(s) 1 x M.2 Anchor 1 x Supporting DVD User manual |
Dimension | 22.6 cm x 20.3 cm |
Warranty | 3 Years |